Osteosarcoma is a common form of bone cancer. This cancer usually begins in cells called osteoblasts, which make bones. This type of cancer can spread to other parts of the body.
The cause is not known. There may be a genetic link.
Risk factors include: Gender: teen boys (may affect them during their growth spurt)
Genetic conditions (eg,
, Li-Fraumeni syndrome)
Symptoms may include: Swelling or a lump at the location of the tumor (usually affects longer bones)Pain at the tumor locationDifficulty moving the affected limbLimpingDeep bone pain severe enough to wake up your childBone fractures
If your child has any of these symptoms, talk to the doctor right away.
The doctor will ask about your child’s symptoms and do a medical history. A physical exam will also be done. Tests may include: Blood testsX-ray
—a test that uses radiation to take a picture of bones
—a test that looks for bone tumors
—a type of x-ray that uses a computer to make pictures of bones
—a test that uses magnetic waves to make pictures of bones
—removal of a sample of bone tissue to test for cancer cells
Once cancer is found, the doctor will do staging tests to find out if the cancer has spread. Treatment depends on the stage and location of the cancer. Talk with the doctor and healthcare team about the best treatment plan for your child. Options include:
is the use of drugs to kill cancer cells. The drugs enter the bloodstream and travel through the body killing mostly cancer cells.
Surgery involves the removal of the tumor, nearby tissues, and nearby lymph nodes. Surgery may require
amputation of the limb
. Whenever possible, the doctor will try to remove the cancerous part of the bone without amputating. Sometimes, treatment with chemotherapy can help avoid the need for amputation.
With radiation therapy, radiation is directed at the tumor to kill the cancer cells.
Radiation of Tumor
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There is no known way to prevent this type of bone cancer.
Nemours Foundation. Childhood cancer: osteosarcoma. Kids Health website. Available at:
http://kidshealth.org/parent/medical/cancer/cancer_osteosarcoma.html#. Updated January 2008. Accessed July 7, 2010.
Osteogenic sarcoma. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated June 30, 2010. Accessed July 7, 2010.
Osteosarcoma. Children’s Hospital Boston website. Available at:
http://www.childrenshospital.org/az/Site1077/mainpageS1077P0.html. Accessed July 7, 2010.
Last reviewed May 2014 by Mohei Abouzied, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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